ZIF-8 Synthesis through Ball Milling – Greener Alternatives for ZIF Synthesis

My study explores various solvents, catalysts, and linkers to improve the efficiency, safety, and environmental impact of ZIF synthesis. ZIFs, a class of nanoporous materials, have potential in targeted drug delivery and gas storage. Enhancing traditional synthesis is crucial for making ZIFs viable for large-scale applications. Ball milling, using mechanical force, proved faster and more energy efficient than traditional methods, and ammonium salts increased the yield. Methanol emerged as a safer but less effective solvent than DMF. Solvents with polarity similar to reactants were most effective, suggesting further investigation into suitable solvent alternatives is needed. This research indicates great potential for more sustainable and efficient ZIF synthesis using ball milling and ammonium salts.